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The National High School Journal of Science

The Role of FYN Inhibition and Knockdown in Determining Podocyte Cell Size and Actin Cytoskeleton

Daleep Grewal Roslyn High School Round Hill Road Roslyn Heights, NY 11577 Peer Reviewer: Himanshi Verma Pro Reviewer: Dr. Madhav C Menon Abstract Chronic kidney disease prevalence in the United States is expected to rise substantially, indicating that kidney transplantation is sub-par and that it is necessary to find biomarkers of the disease. Shroom3 was identified as a gene whose expression in renal allografts correlates with renal function decline; this is significant as 40% of transplant patients were found to Read more…

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Implementation of a fluorescent image background removal algorithm adopted from optical spectrum baseline retrieval with iterative average

Alex Y. Chen Urbana High School, Ijamsville, MD 21754, USA Peer Reviewer: Maren Sophie Sautter Professional Reviewer: Emma Regentova      Abstract: Fluorescent microscopy imaging is a powerful tool used to visualize intracellular spatial distribution. A fluorescent image inevitably carries fluorescent background which comes from multiple sources, so an effective background removing method is desirable before image analysis is performed. I propose to adopt an optical spectral baseline retrieval method called iterative average (IA) for fluorescent background removal in fluorescent images. The Read more…

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An Examination of the Effectiveness of Honey as an Antimicrobial Agent against S. pyogenes and C. perfringens under Anaerobic Conditions

Rose Evard* * Corresponding author at Middlesex Community College, Bedford, MA 01730 Peer Reviewer: Akhila Gundavelli Professional Reviewer: Kimberly Gonzalez Abstract          Since their discovery, antibiotics have been a major factor in modern medicine; however, they are overused, leading to a growing list of antibiotic resistant bacteria [1].  An alternative method for treatment of bacterial infections is honey. Honey’s natural antimicrobial properties—specifically its high concentration of sugar and hydrogen peroxide, as well as its acidic pH, and the presence of Read more…

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Special Relativity and Newtonian Mechanics beyond the Speed of Light and for Objects with Negative Mass

Abrar Syed McLean High School Contact: [email protected] Peer Reviewer: Cole Johnson Professional Reviewer: Mohsina Asif Abstract: The following paper discusses the effects of special relativity and Newtonian mechanics on particles theoretically traveling faster than the speed of light, and for objects with negative mass. The primary focus will be on deriving a new gamma value for Lorentz transformations which works for velocities exceeding the speed of light (c). Later parts of this paper will discuss possible ways in which an object Read more…

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Carbon Nanotube Membranes for Salt Rejection in Water Purification

Author: Caitlyn Brahim Peer Reviewer: Annasimone Andrawis Professional Reviewer: Thomas D. Lazzara Abstract Worldwide, about 700 million people have no access to clean water or sanitation. In 10 years, this number is expected to expand to 1.8 billion, or roughly one-fourth of the global population. To address this growing crisis, scientists have developed high performance synthetic membranes as a viable means of water purification. The development of these advanced membrane technologies with controlled and novel pore architectures is important for Read more…

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