Abstract In the United States, drug abuse continues to be a crucial public health challenge, especially in major cities like New York City. The impact of drug activity isn’t simply confined to its clinical effects, and public drug use visibility undermines community safety and well-being. While supervised consumption sites (SCS) have been reported to reduce […]

Abstract Pollen grains are the natural starting point for microcapsules and biomaterials used in diverse engineering applications. Defatting, solvent extraction and acid/alkaline treatment are standard techniques for converting native pollen into “inert” materials through removing internal biological components. However, the common assumption that physiochemically treated pollen particles are necessarily biologically inactivated is questionable. Pollen grains […]

Abstract Pyruvate Dehydrogenase Complex Deficiency (PDCD) is a rare, often fatal genetic disorder that affects carbohydrate metabolism by disrupting the conversion of pyruvate into acetyl-CoA. PDCD is primarily caused by pathogenic variants in any genes encoding Pyruvate Dehydrogenase Complex (PDC) subunits, typically mutations in the pyruvate dehydrogenase E1 subunit alpha 1 (PDHA1) gene. Current treatment […]

Abstract The gut–brain axis is an expanding area of mental health research, representing the connection between the gastrointestinal microbiota and neural, immune, and endocrine pathways that influence mood and behavior. There is emerging evidence pointing to disruptions in the gut microbiome that may contribute to depression and anxiety. Additionally, research indicates that interventions targeting the […]

Abstract IgA nephropathy (IgAN) causes an inflammation of the glomeruli by an accumulation of Immunoglobulin A antibodies, and there are many patient characteristics that have been found to highly correlate with and potentially further advance the pathogenesis of this disease. In this study, we built models studying whether IgAN patient characteristics such as Age, Sex, […]