In Silico Analysis and Docking Study on a Potential Wild-Type, Tumor Suppressor Protein P53 Activator using Thymoquinone

Ahnaf Khan Student, Thomas Jefferson High School for Science and Technology, Alexandria, Virginia ABSTRACT: p53 is a potent tumor suppressor protein that is frequently mutated or inactivated in almost 50% of all human cancers. These statistics, as well as essential functions of p53 in maintaining normal cell cycle and apoptosis, impose the urge to extend new methods for making p53 a target for new molecular-based therapies. The purpose of this study was to analyze the […]