The Effect of Exercise on Regulatory T Cell Populations in Rat Mammary Adenocarcinoma Tumor and Spleen Samples using Foxp3 and CD25

The Effect of Exercise on Regulatory T Cell Populations in Rat Mammary Adenocarcinoma Tumor and Spleen Samples using Foxp3 and CD25 Sharonya Battula ABSTRACT In healthy individuals, regulatory T cells (Tregs) suppress self-reactive lymphocytes to prevent autoimmune disease; however, in cancer patients, Tregs also serve a protumorigenic function, as their presence in the tumor microenvironment interferes with the ability of other lymphocytes to target and eliminate cancer cells. Because the progression of cancer is largely […]

Ewing Sarcoma

Ewing Sarcoma by Mafalda von Alvensleben Ewing Sarcoma, though unbeknownst to most of the general population, is a type of pediatric cancer that affects the soft tissue or bone. Approximately 225 people in the United States are diagnosed with this disease each year, primarily those between the ages of ten and twenty, making it comprise about 1% of all pediatric cancers. Ewing Sarcoma is typically discovered via radio-imaging techniques and confirmed by a biopsy of the […]

Customized Chemotherapy Regime Based on Blood Vessels with Different Number of Stenosis

  Yifan Wang 1, Will Cao 2 1 Indian Springs School, 190 Woodward Drive, Indian Springs, AL 35124, USA E-mail: yifan.wang@indiansprings.org 2 Department of Biomedical Engineering, Duke University, Durham, NC 27705, USA Email: yangxiaolu.cao@duke.edu Abstract Chemotherapy has been an effective approach to treat cancer; however, chemotherapy's effectiveness could be influenced by many unknown and often neglected factors. In this project, we build mathematical models in MATLAB to explain what impact will blood vessel with stenosis […]

Examining the Effect of TRIP13 Over Expression on Cancerous Aneuploidy

        This Research was completed with the University of Toledo Sanjay Jinka Anthony Wayne High School 2801 W Bancroft St, Toledo, OH 43606 ABSTRACT Nineteen million people are projected to have cancer by 2024 so understanding tumorigenesis is of foremost importance. Of solid tumors, 90 percent are aneuploid, signifying an abnormal number of chromosomes usually caused by malfunctioning mitotic checkpoints. TRIP13 AAA-ATPase is a crucial silencing protein in this checkpoint. Therefore, it was hypothesized that TRIP13 […]