Gene Therapy for Sensorineural Hearing Loss

By Eshaan Soman Abstract Sensorineural hearing loss is a serious impairment that deprives more than 360 million people worldwide from one of their vital senses. Furthermore, more than 1.1 billion people are becoming increasingly susceptible to the condition as well (“Deafness and Hearing Loss”). Though common, this medical disability has no cure yet. However, gene therapy is an emerging treatment that is being developed to tackle the root causes of this morbidity. Introduction Humans interpret […]

Phytoremediation: Utilizing Hyperaccumulator Plants to Extract Toxic Chemical Waste from Soil & Groundwater

By Luci C. Edenlord Soil and groundwater contaminants represent one of the most harmful pollutants in the world by destroying habitats, wrecking ecosystems, poisoning clean water and being a huge detriment to human and animal health. Imagine that by just planting a few simple seeds, the destruction would melt away without negatively affecting human and animal health and the environment. One field of sunflowers (Helianthus) has the capability to extract industrial contaminants such as lead […]

Customized Chemotherapy Regime Based on Blood Vessels with Different Number of Stenosis

  Yifan Wang 1, Will Cao 2 1 Indian Springs School, 190 Woodward Drive, Indian Springs, AL 35124, USA E-mail: yifan.wang@indiansprings.org 2 Department of Biomedical Engineering, Duke University, Durham, NC 27705, USA Email: yangxiaolu.cao@duke.edu Abstract Chemotherapy has been an effective approach to treat cancer; however, chemotherapy's effectiveness could be influenced by many unknown and often neglected factors. In this project, we build mathematical models in MATLAB to explain what impact will blood vessel with stenosis […]

Development of a Small Molecule C-X-C Chemokine Receptor Type 4 (CXCR4) Agonist

Authorship: Tiffany Ding*, Susriya Gangireddy*, Andrew Shum, Richard J. Miller** *These authors contributed equally **Corresponding author: r-miller10@northwestern.edu Student: Illinois Math and Science Academy, 1500 Sullivan Road, Aurora, IL Mentor: Northwestern University-Feinberg School of Medicine, 645 N Michigan Avenue, Suite 900, Chicago, IL Abstract: Activation of the C-X-C chemokine receptor type 4 (CXCR4) by its natural ligand stromal cell-derived factor 1 (SDF-1) is known to be involved in a number of vital physiological processes such as […]

Role of Telomeres in Aging

HoJun Kweon* and HyoJu Kweon Daegu International School, 101-dong 2201-ho, 10, Palgong-ro 53-gil, Dong-gu, Daegu, Republic of Korea Jinkyoung (May) Lee Yongsan International School of Seoul, San 10-213, Hannam 2 dong, Yongsan-ku, Seoul, Republic of Korea Abstract At the ends of eukaryotic chromosomes are telomeres, which play a central role in the protection of genetic data and the enabling of cell division. Telomeres modify the cellular response to growth and stress based on various hereditary […]