Secondary Structure Changes caused by ADAR Protein in the Development of ALS, Leukemia, and Schizophrenia

By Kavya Anjur Metea Valley High School, IL Abstract This experiment compared specific protein sequences affected by the misediting  of  ADAR  which then  resulted in specific misalignments on the protein’s structure and folding. The information was analyzed for relationships between different mutations to help regulate genes and prevent diseases such as ALS, leukemia, and schizophrenia related to the misediting  of the ADAR protein. The sequences of the GluA2 Isoforms, PTPN6 protein, and 5-HT(2C) protein were […]