Effects of Nitro-Oleic Acid on RAW-Blue™ Cell Activity

by David J Portnoy Abstract Chronic inflammatory disease affects millions of individuals around the world. Inflammation occurs when foreign bacteria bind to receptors on cell surfaces, thereby inducing macrophage activation. This series of actions leads to the release of pro-inflammatory molecules, like nitric oxide (NO), resulting in inflammation. A major driver of inflammatory responses is the transcription factor nuclear factor kappa-light-chain-enhancer of activated B cells (NF-kB). This study seeks to examine the interaction between OA-NO2 […]

Harvesting Kinetic Energy Through Linear Alternation

Harvesting Kinetic Energy Through Linear Alternation by Seth Woodbury, Lochlyn Reed, and Max Eyster Abstract The focus of this research was to harness human kinetics as an alternative energy source. Two body parts (shoulder and calf) of 20 randomly selected subjects were tested with a modified accelerometer that measured movement in all three dimensions which ultimately concluded the calf generates the most movement. A linear alternator was created to fit on the calf and utilize […]

Implementation and Feasibility of Artificial Muscles in Prosthesis

Implementation and Feasibility of Artificial Muscles in Prosthesis by Brady Russell Abstract Artificial Muscles (electroactive polymers, dielectric elastomers, etc.) have been looked at for potential use in prosthesis and orthotics. The purpose of this research is to look at the feasibility of using these current technologies, especially in their respective ability for load bearing capacity and power consumption. My focus was on three types of artificial muscles: Peano-HASEL actuators, McKibben actuators, and dielectric elastomers. All of […]

Lactose Assay using Spectrophotometry to detect and analyze Competitive Inhibition from ONPG

By: Melissa Manetsch and Maggie Shutts Abstract: The purpose of this research is to determine if it is possible to develop a qualitative assay to assess whether a sample containing an unknown concentration of lactose is below or above the threshold of an individual’s tolerance. Our research would then be able to determine if it is valid to create an assay in which quantifying the effects of varying concentrations of lactose on ONPG due to […]