Prediction of Critical Intracranial States through Medical Signal Processing

Tejas Thvar1, Abhejit Rajagopal 2 1Mountain View High School, 3535 Truman Ave, Mountain View, CA 94040 e-mail address: 2Department of Electrical and Computer Engineering, University of California, Santa Barbara, CA, 93106 ABSTRACT:    Intracranial hypertension and epileptic seizures are debilitating conditions. While surgical intervention can be lifesaving in these critical brain states, current state of the art monitoring/diagnostic techniques are inadequate as they detect these events after they occur. It is critical to develop predictive […]

SLC1A1, SLC6A2, SLC6A3, and SLC6A4: Novel Candidate Genes in Major Depressive Disorder

By Sriya Kudaravalli Within the past two decades, a lot of research has been done on the genetics behind cancer and diseases such as cystic fibrosis, anemia, Huntington’s disease, Down Syndrome, Turner Syndrome, and autism just to name a few. However, the medical field lacks sufficient research on the genetics behind psychiatric disorders, especially mood disorders such as Major Depressive Disorder (MDD), since the role of genetics in mood disorders has only recently been acknowledged. Before, […]

A Prudent and Democratic Approach to Regulating CRISPR/Cas 9

By Daniel Cui Purpose The purpose of this study is to determine a judicious and egalitarian method of regulating the recently discovered CRISPR/Cas9 gene-editing biotechnology and determining some of the major themes in its relevant ethical, social, legal, and religious issues that could potentially have a major impact on humanity in the future. Conclusions were drawn based on the 1975 Asilomar Conference regarding recombinant DNA and analyzing the ethical, social, legal, and religious implications. Because […]

Using Resting-State Functional Connectivity Within the Basal Ganglia as a Biomarker for Symptoms of Parkinson's Disease

Neal Modi*, Tianlin Yuan*, Dr. Todd Parrish**, Dr. Xue Wang**, Dr. Darren Gitelman** * Illinois Mathematics and Science Academy ** Northwestern University, Feinberg School of Medicine, Department of Radiology Abstract Parkinson’s disease (PD) is a chronic movement disorder that occurs when nigrostriatal dopaminergic neurons within the Basal Ganglia Network (BGN) are damaged or destroyed, causing motor and cognitive disabilities. Motor disabilities can be measured by the Unified Parkinson’s Disease Rating Scale (UPDRS-III). PD currently has […]

In Silico Analysis and Docking Study on a Potential Wild-Type, Tumor Suppressor Protein P53 Activator using Thymoquinone

Ahnaf Khan Student, Thomas Jefferson High School for Science and Technology, Alexandria, Virginia ABSTRACT: p53 is a potent tumor suppressor protein that is frequently mutated or inactivated in almost 50% of all human cancers. These statistics, as well as essential functions of p53 in maintaining normal cell cycle and apoptosis, impose the urge to extend new methods for making p53 a target for new molecular-based therapies. The purpose of this study was to analyze the […]