Using Resting-State Functional Connectivity Within the Basal Ganglia as a Biomarker for Symptoms of Parkinson's Disease

Neal Modi*, Tianlin Yuan*, Dr. Todd Parrish**, Dr. Xue Wang**, Dr. Darren Gitelman** * Illinois Mathematics and Science Academy ** Northwestern University, Feinberg School of Medicine, Department of Radiology Abstract Parkinson’s disease (PD) is a chronic movement disorder that occurs when nigrostriatal dopaminergic neurons within the Basal Ganglia Network (BGN) are damaged or destroyed, causing motor and cognitive disabilities. Motor disabilities can be measured by the Unified Parkinson’s Disease Rating Scale (UPDRS-III). PD currently has […]

In Silico Analysis and Docking Study on a Potential Wild-Type, Tumor Suppressor Protein P53 Activator using Thymoquinone

Ahnaf Khan Student, Thomas Jefferson High School for Science and Technology, Alexandria, Virginia ABSTRACT: p53 is a potent tumor suppressor protein that is frequently mutated or inactivated in almost 50% of all human cancers. These statistics, as well as essential functions of p53 in maintaining normal cell cycle and apoptosis, impose the urge to extend new methods for making p53 a target for new molecular-based therapies. The purpose of this study was to analyze the […]

Deep Sea Oil Trap: An Underwater Cleanup System for Platforms and Ships to Contain and Recapture Oil Plumes

  By: Sachin Narayan Abstract: Underwater oil plumes are an accumulation of oil microdroplets that, due to a number of factors (namely size, temperature, pressure, and currents), do not rise to the surface (Zhao, 2016). This research aims to better understand underwater oil plume dynamics and forces and test reusable materials and processes that effectively recapture the oil without causing further environmental damage. The work concluded that a two-part system involving containment and recapture provides […]

The Role Of Neural Connections In Physical Behaviors Associated With Dance

By Ritika Miryala ABSTRACT The purpose of this study was to investigate the relevance of neural circuits in regulating physical behaviors. The human brain is an intricate network that constantly forms new neural connections which encode various physical behaviors. The more frequently a physical behavior is performed, the stronger its corresponding neural connection becomes. As a result, the operational definition of neural connection was applied to hypothesize that individuals with more experience in a physical […]