Behind the Mechanics of Brain Injury: The Buckling of Microtubules in Axons

The mechanics of traumatic brain injury (TBI) are beginning to be unveiled.  A team at the University of Pennsylvania, led by Douglas Smith, has discovered exactly what happens when a brain experiences a sudden blow.  The team observed microtubules snapping inside the axons, the long fibers that extend from brain cells. Microtubules are the “superhighways of protein transfer,” according to Douglas Smith ((Sanders, Laura. "Brain at the Breaking Point." ScienceNews 13 Mar 2010: n. pag. […]