Shedding Light on Genomic Dark Matter: An Introduction to Long Noncoding RNA

Abstract While the central dogma of biology describes RNA’s role as a messenger to relay DNA code into protein production, not all RNA is directly involved in protein synthesis. Within the past few decades, largely due to the availability of whole-genome sequences and emerging RNA sequencing technologies, research has expanded to focus on RNA that does not code for proteins, or noncoding RNA. While scientists have known about noncoding RNAs (ncRNAs), such as ribosomal RNA […]