Chemokines: A novel method of probing the active site structure of membrane proteins

A novel method of probing the active site structure of membrane proteins just emerged in a recent finding by a European team of scientists. In a paper titled “Oxovanadium(IV) Cyclam and Bicyclam Complexes: Potential CXCR4 Receptor Antagonists” ((Inorg. Chem., 2010, 49 (3), pp 1122–1132)), researchers Allison Ross, Dinesh C. Soares, Danielle Covelli, Christophe Pannecouque, Laura Budd, Anna Collins, Neil Robertson, Simon Parsons, Erik De Clercq, Pierre Kennepohl and Peter J. Sadler isolated vanadyl xylylbicyclam complexes […]