The Imperative Need to Consider the Bioethics of CRISPR-Cas9 Technology

  Jihee Yoon University High School, CA   Abstract The CRISPR-Cas9 technology is the latest and most controversial gene editing technology available today. It allows for precise editing of DNA, which is also known as the genetic code of the human body. While CRISPR seems to possess great potential to solve genetic mutations, ethicists and researchers still believe this technology should not be applied as of now due to its insufficient experimentation, significant consent limitations, […]

Secondary Structure Changes caused by ADAR Protein in the Development of ALS, Leukemia, and Schizophrenia

By Kavya Anjur Metea Valley High School, IL Abstract This experiment compared specific protein sequences affected by the misediting  of  ADAR  which then  resulted in specific misalignments on the protein’s structure and folding. The information was analyzed for relationships between different mutations to help regulate genes and prevent diseases such as ALS, leukemia, and schizophrenia related to the misediting  of the ADAR protein. The sequences of the GluA2 Isoforms, PTPN6 protein, and 5-HT(2C) protein were […]

On the Development of Q. alba as an Oral Care Product: A Comparison with T. chebula by TLC

Tejas Thvar Mountain View High School, Mountain View, CA Abstract Natural remedies for oral care have been used since ancient times.  The fruit of Terminalia Chebula (T. chebula), a tropical deciduous tree, has been widely used in oral care in tropical countries. In more recent studies the antimicrobial and antibacterial properties of T. chebula have been adequately demonstrated. T. chebula, however, grows only in specific locations in South Asia and not easily available in other […]

Lipopolysaccharide-Induced Acute Inflammation in Mouse Lung

Lipopolysaccharide-Induced Acute Inflammation in Mouse Lung Robert Xiaxuan Lao Mentor: Professor Hartmut Grasemann, MD 1.0 Abstract 1.1 Rationale Lipopolysaccharides (LPS) from gram-negative bacteria have the ability to induce immune responses in humans. The presence of cells, such as macrophages and neutrophils, as well as production of nitric oxide (NO) is increased in such circumstances. We studied the effects that LPS has on pulmonary function in mice, to serve as a basis for future implementations of […]