Gene Therapy for Sensorineural Hearing Loss

By Eshaan Soman Abstract Sensorineural hearing loss is a serious impairment that deprives more than 360 million people worldwide from one of their vital senses. Furthermore, more than 1.1 billion people are becoming increasingly susceptible to the condition as well (“Deafness and Hearing Loss”). Though common, this medical disability has no cure yet. However, gene therapy is an emerging treatment that is being developed to tackle the root causes of this morbidity. Introduction Humans interpret […]

Comprehensive Review of Exchange-Correlation Functional Methods

Ashwin Inala NCSSM Online North Carolina School of Science and Mathematics Durham, North Carolina February 25, 2017 Abstract: Density functional theory is a computational technique of using elec- tron density, not wavefunction, to predict properties of molecular systems. Over the years, many scientists, such as Pierre Hohenberg, Erwin Schrodinger, and Walter Kohn, have contributed to the fast growth of density functional theory. To find the energy of system, scientists must approximate the exchange-correlation functional. The […]

Middle East Respiratory Syndrome Coronavirus (MERS-CoV)

Middle East Respiratory Syndrome Coronavirus (MERS-CoV) From Transmission to Novel Treatments Abstract: The Middle East respiratory syndrome coronavirus is one of the recently discovered respiratory illnesses, in human beings. This disease was first identified in Saudi Arabia, in 20128. It has since spread to several other countries, such the Republic of Korea, causing a widespread panic. However, with the rise of modern treatments and preventions, new novel techniques will be developed and will lead to […]

Development of a Small Molecule C-X-C Chemokine Receptor Type 4 (CXCR4) Agonist

Authorship: Tiffany Ding*, Susriya Gangireddy*, Andrew Shum, Richard J. Miller** *These authors contributed equally **Corresponding author: r-miller10@northwestern.edu Student: Illinois Math and Science Academy, 1500 Sullivan Road, Aurora, IL Mentor: Northwestern University-Feinberg School of Medicine, 645 N Michigan Avenue, Suite 900, Chicago, IL Abstract: Activation of the C-X-C chemokine receptor type 4 (CXCR4) by its natural ligand stromal cell-derived factor 1 (SDF-1) is known to be involved in a number of vital physiological processes such as […]