Computational Analysis of Drug Therapy Options for Glioblastoma

Kriti Agrawal Centerville High School Abstract Glioblastoma (GBM) is the most common primary brain tumor in the US and European countries and also the deadliest. ¬†Glioblastoma cells exhibit a different gene expression profile from normal cells. There are 601 known mutations in GBM tumors. The aim of this study was to identify the most important proteins in the glioblastoma pathway that lack drug treatments. A total of 15 proteins were identified as pathway starters or […]

A Three Year Study of an Isolated Brook Trout Population in the Eastern Adirondacks: Sustainability, Propagation and Genetics

Over the past several years changing weather patterns have led to costly and destructive storms that are damaging both environmentally and economically. In 2011, Hurricane Irene was an unusual storm because it struck the eastern Adirondack Mountains in New York. The Adirondack region mainly relies on tourists to make money and fishing is a large part of what draws people to this region. Three years ago, a study was started to explore the impact of […]

Alcoholism: A Neurological Perspective

After an intensive course regarding alcoholism with Dana Most and Dr. Adron Harris in the Waggoner Center for Alcohol and Addiction Research at the University of Texas at Austin, alcoholism, its causes, diagnosis, prognosis, and FDA-approved treatments were investigated. Here is the report written under their guidance. Alcoholism is one of the foremost problems in society today. The DSM-5 manual helps doctors tell what disease you may have and better allows them to treat you […]

Assessing the Development of Artificial Intelligence Technologies In Radiation Therapy and Targeting Irregular Masses

Eric Bear, Jessica Singh, and Michael Wahrman   ABSTRACT The purpose of this paper is to evaluate the use of artificial intelligence in the medical use of particle accelerators for both treatment (radiation therapy) and imaging. We will first discuss the implications of artificial intelligence (AI) on particle accelerators, starting with basic control mechanisms and then moving to complex systems such as neural networking. AI has the potential to increase efficiency and precision in all […]

A New Signaling Pathway in Diamond Blackfan Anemia

Sriya Kudaravalli Diamond Blackfan Anemia (DBA) is blood disease in which the bone marrow malfunctions and fails to make enough erythrocytes, or red blood cells. Inherited in an autosomal dominant pattern, DBA affects approximately five to seven million infants globally, and about half of the DBA patients possess physical abnormalities, such as microcephaly, hypertelorism, Ptosis, micrognathia, webbed neck, absent thumbs, cataracts, and glaucoma. In addition, affected patients have an increased risk of developing acute myeloid […]

Innovative New Technology Attempting to Reduce Hospital Associated Infections

Kenneth Trang Introduction Today, the modern American is more likely than ever before to visit a hospital, local doctor, or any healthcare provider. In fact, 83% of Americans (268 million) visited a healthcare professional in 2015 ((Summary Health Statistics: National Health Interview Survey. Centers for Disease Control and Prevention. 2015)). However, while hospitals do have general health benefits, visiting one exposes patients to a new risk: healthcare associated infections (HAIs), also known as nosocomial infections. […]