Computational Analysis of Drug Therapy Options for Glioblastoma

Kriti Agrawal Centerville High School Abstract Glioblastoma (GBM) is the most common primary brain tumor in the US and European countries and also the deadliest. ¬†Glioblastoma cells exhibit a different gene expression profile from normal cells. There are 601 known mutations in GBM tumors. The aim of this study was to identify the most important proteins in the glioblastoma pathway that lack drug treatments. A total of 15 proteins were identified as pathway starters or […]

A Three Year Study of an Isolated Brook Trout Population in the Eastern Adirondacks: Sustainability, Propagation and Genetics

Over the past several years changing weather patterns have led to costly and destructive storms that are damaging both environmentally and economically. In 2011, Hurricane Irene was an unusual storm because it struck the eastern Adirondack Mountains in New York. The Adirondack region mainly relies on tourists to make money and fishing is a large part of what draws people to this region. Three years ago, a study was started to explore the impact of […]

Alcoholism: A Neurological Perspective

After an intensive course regarding alcoholism with Dana Most and Dr. Adron Harris in the Waggoner Center for Alcohol and Addiction Research at the University of Texas at Austin, alcoholism, its causes, diagnosis, prognosis, and FDA-approved treatments were investigated. Here is the report written under their guidance. Alcoholism is one of the foremost problems in society today. The DSM-5 manual helps doctors tell what disease you may have and better allows them to treat you […]

A New Signaling Pathway in Diamond Blackfan Anemia

Sriya Kudaravalli Diamond Blackfan Anemia (DBA) is blood disease in which the bone marrow malfunctions and fails to make enough erythrocytes, or red blood cells. Inherited in an autosomal dominant pattern, DBA affects approximately five to seven million infants globally, and about half of the DBA patients possess physical abnormalities, such as microcephaly, hypertelorism, Ptosis, micrognathia, webbed neck, absent thumbs, cataracts, and glaucoma. In addition, affected patients have an increased risk of developing acute myeloid […]

Innovative New Technology Attempting to Reduce Hospital Associated Infections

Kenneth Trang Introduction Today, the modern American is more likely than ever before to visit a hospital, local doctor, or any healthcare provider. In fact, 83% of Americans (268 million) visited a healthcare professional in 2015 ((Summary Health Statistics: National Health Interview Survey. Centers for Disease Control and Prevention. 2015)). However, while hospitals do have general health benefits, visiting one exposes patients to a new risk: healthcare associated infections (HAIs), also known as nosocomial infections. […]

The Retrospective Overview on Bioengineering Application of Induced Pluripotent Stem Cell

Min Jae Kim Keywords: iPS Cell, ES cell, Regenerative Medicine, Bioengineering, Organ Transplant, Stem Cell, Yamanaka Shinya, disease model Abstract The creation of the first Induced-Pluripotent Stem cell (iPS cell) from mice fibroblast cells in 2006 was promising. Subsequently in 2007, attempt to induce adult human fibroblasts into IPS cell was successful (Takahashi et al., 2007), thus opening its universal application into regenerative medicine. From this innovation, the continuous studies have allowed the iPS cell […]